Harvard-backed study finds Sadhguru's Samyama Sadhana meditation slows brain aging

Sadhguru is earning his Harvard-backed validation.

In a first-of-its-kind discovery, Harvard-affiliated researchers have confirmed that the ancient yogic practice of Samyama Sadhana meditation may prove helpful to reverse the brain's biological age.


What does the study say?

The study, conducted by experts from Massachusetts General Hospital and Beth Israel Deaconess Medical Center (both tied to Harvard Medical School), focused on individuals practising the Samyama Sadhana technique, an intensive 8-day meditation retreat designed by spiritual leader Sadhguru, during a retreat.

Our new study in Mindfulness (https://t.co/mWcZsLppqg) shows advanced meditators have a 5.9-year younger brain age! Meditation may hold the key to reversing brain aging. Proud to be part of this groundbreaking research@HarvardHealth @harvardmed @SadhguruJV @InnerEngineering pic.twitter.com/9gwlIv4XWK

— Dr. Bala Subramaniam (@balachundhar) May 17, 2025

The research involved participants who underwent resting-state functional magnetic resonance imaging (rs-fMRI) before and after the Samyama program. The scans revealed significant changes in brain network connectivity, particularly between the salience network (SN) and the default mode network (DMN). These networks are associated with self-awareness, attention, and emotional regulation. Enhanced connectivity between these networks is linked to improved mindfulness and cognitive function.

The study has revealed that advanced yogic meditation may reverse brain aging by an average of 5.9 years. In some cases, researchers observed that the difference went beyond a decade.


The Samyama Sadhana Program:

According to Isha Foundation, Samyama Sadhana is an advanced meditation program that immerses participants in complete silence for eight days, with long hours of intense meditation. The program is designed to help individuals transcend the limitations of the body and mind, leading to heightened states of consciousness and deep meditative experiences.

It is wonderful that modern science is able to identify and measure the impact of the subjective sciences on the human mechanism. Enhancing the exuberance & vibrancy of the human mechanism will naturally slow the aging process & cognitive decline. Every human being must invest in… https://t.co/lEDlPMImcc pic.twitter.com/8ynup9ZGuJ

— Sadhguru (@SadhguruJV) May 18, 2025

Conducted at the Isha Yoga Center in India and the Isha Institute of Inner Sciences in the USA, Samyama Sadhana offers a unique opportunity for profound inner transformation.


Implications for brain health

The findings suggest that engaging in intensive meditation practices like Samyama Sadhana can have a rejuvenating effect on the brain, potentially reversing age-related cognitive decline. This research adds to a growing body of evidence supporting the neuroplastic benefits of meditation. Previous studies have shown that meditation can increase cortical thickness in areas related to attention and sensory processing, which typically thins with age.



What is reverse brain aging?

While "reversing" brain aging in the sense of returning to a younger state is an ambitious goal, several strategies can significantly improve brain health and slow down the aging process. These include adopting a healthy lifestyle, engaging in regular mental and physical activities, and managing chronic conditions.


Some strategies to improve brain health and slow down aging:

Healthy lifestyle:

Diet: A diet rich in fruits, vegetables, whole grains, nuts, and fish, like the Mediterranean-DASH diet, can provide brain-healthy nutrients.

Exercise: Regular physical activity, including both aerobic and strength training, improves blood flow to the brain, boosts cognitive function, and can even lead to the growth of new brain cells.

Sleep: Adequate sleep is crucial for brain health, as it allows the brain to clean itself of waste products and consolidate memories.

Social engagement: Staying socially active can stimulate the brain and reduce the risk of cognitive decline.

Mental stimulation:

Engage in challenging activities: Learning new skills, playing games, and reading can keep the brain active and improve cognitive function.

Lifelong learning: Continuously learning new things can create new neural pathways and improve cognitive flexibility.

Manage chronic conditions:

Blood pressure and blood sugar: Managing hypertension and diabetes is crucial for preventing cognitive decline, as these conditions can damage blood vessels and lead to brain damage.

Other chronic conditions: Addressing any underlying health issues can contribute to overall brain health.